Renin Angiotensin Signaling in Normal Pregnancy and Preeclampsia
نویسندگان
چکیده
منابع مشابه
Investigation of ANP Plasma Concentration in Normal Pregnancy and Preeclampsia
با وجود شواهد روزافزونی که بیانگر نقش احتمالی ANP در هموستاز طبیعی مایعات بدن است، اما هنوز اهمیت نقش این پیتید در سلامت و بیماری بدرستی مشخص نیست. بر اثر ازدیاد فشار دهلیزی و تعداد انقباضات آن، ANP از میوسیت های دهلیزی ترشح می شود. تزریق مقادیر زیادی از ANP صناعی به انسان و حیوان سبب کاهش فشار سیستمیک دهلیزی و افزایش دفع سدیم و برقراری دیورز می گردد. مطالعات اخیر بر روی تأثیر تزریق ANP صناعی ...
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Unilateral ureteral obstruction (UUO) is a clinical scenario that leads to obstructive nephropathy. UUO alters the expression of many mediators in the ipsilateral kidney. Renin-angiotensin system (RAS) is involved in UUO. Angiotensin II (Ang II) and angiotensin 1-7 (Ang 1-7) as the main arms of RAS influence kidney function which may alter by UUO. Ang II via Ang II receptor subtypes I (AT1R) ...
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Most studies that have attempted to distinguish pregnancy-induced hypertension from chronic hypertension in pregnancy include arbitrary clinical definitions and morphological reports based on renal biopsy. To evaluate whether these conditions have different responses to stimuli to the renin-angiotensin-aldosterone system, we studied four normal nonpregnant women, eight normal pregnant women, 10...
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ژورنال
عنوان ژورنال: Seminars in Nephrology
سال: 2011
ISSN: 0270-9295
DOI: 10.1016/j.semnephrol.2010.10.005